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主要文件

SML0100

Sigma-Aldrich

GYY4137二氯甲烷配合物

≥98% (HPLC), powder, H₂S donor

别名:

与吗啉(1:1)形成的化合物, 吗啉-4-鎓4-甲氧基苯基(吗啉代)二硫代磷酸二氯甲烷配合物, 对-(4-甲氧基苯基)-P-4-吗啉基-二硫代磷酸

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50 G
¥6,984.41
100 G
¥12,349.49
6 X 100 G
¥50,600.71

¥6,984.41


国内现货,预计发货时间2025年4月27日详情


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选择尺寸

变更视图
50 G
¥6,984.41
100 G
¥12,349.49
6 X 100 G
¥50,600.71

About This Item

经验公式(希尔记法):
C11H16NO2PS2 · C4H9NO · xCH2Cl2
分子量:
376.47
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.25

¥6,984.41


国内现货,预计发货时间2025年4月27日详情


获取大包装报价

产品名称

GYY4137二氯甲烷配合物, ≥98% (HPLC)

质量水平

方案

≥98% (HPLC)

表单

powder

颜色

white to tan

溶解性

DMSO: ≥3 mg/mL

储存温度

2-8°C

SMILES字符串

ClCCl.S=P(N1CCOCC1)([S-])C2=CC=C(OC)C=C2.C3COCC[NH2+]3

InChI

1S/C11H16NO2PS2.C4H9NO.CH2Cl2/c1-13-10-2-4-11(5-3-10)15(16,17)12-6-8-14-9-7-12;1-3-6-4-2-5-1;2-1-3/h2-5H,6-9H2,1H3,(H,16,17);5H,1-4H2;1H2

InChI key

PKLNNEJKTAMITC-UHFFFAOYSA-N

相关类别

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此商品
G50150G100120U8878
matrix

Agarose

matrix

Agarose

matrix

Agarose

matrix

3% acrylamide, 4% agarose

separation technique

size exclusion (SEC)

separation technique

size exclusion (SEC)

separation technique

size exclusion (SEC)

separation technique

size exclusion (SEC)

matrix active group

polymer

matrix active group

polymer

matrix active group

polymer

matrix active group

polymer

form

slurry

form

slurry

form

slurry

form

aqueous ethanol suspension

technique(s)

LPLC: suitable

technique(s)

LPLC: suitable

technique(s)

LPLC: suitable

technique(s)

LPLC: suitable

storage temp.

room temp

storage temp.

-

storage temp.

-

storage temp.

2-8°C

应用

GYY4137二氯甲烷配合物一直用作非异硫氰酸酯H2S(硫化氢)供体。[1]

生化/生理作用

GYY4137是具有血管扩张和抗高血压活性的H2S的小分子释放剂。H2S是一种重要的生物介质,对神经调节、高血压、炎症和血管张力具有多重作用。 GY4137应该可以用于研究H2S的多种生物效应。
小分子H2S释放剂

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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    Jiateng Hu et al.
    Advanced healthcare materials, 12(28), e2301316-e2301316 (2023-08-02)
    Critical limb ischemia, the final course of peripheral artery disease, is characterized by an insufficient supply of blood flow and excessive oxidative stress. H2 S molecular therapy possesses huge potential for accelerating revascularization and scavenging intracellular reactive oxygen species (ROS).
    Lorenzo Di Cesare Mannelli et al.
    Neuropharmacology, 121, 49-59 (2017-04-23)
    Hydrogen sulfide (H
    Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels.
    Di Cesare Mannelli L et al.
    Neuropharmacology, 121, 49-49 (2007)
    Pooja Malaviya et al.
    Eye and vision (London, England), 11(1), 5-5 (2024-01-17)
    Diabetic retinopathy is a progressive disease, and one of the key metabolic abnormalities in the pathogenesis of diabetic retinopathy, mitochondrial damage, is also influenced by the duration of hyperglycemia. Mitochondrial quality control involves a coordination of mitochondrial dynamics, biogenesis and
    Asefeh Mohammadi et al.
    Scientific reports, 14(1), 12400-12400 (2024-05-30)
    Cryopreservation of sperm can cause oxidative stress and damage, leading to decreased different functional parameters and fertilization potential. In this study, we evaluated two types of H2S donors: NaHS, a fast-releasing donor, and GYY4137, a slow-releasing donor during cryopreservation of

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