推荐产品
质量水平
检测方案
≥98% (HPLC)
形式
powder
颜色
white to tan
溶解性
DMSO: ≥5 mg/mL
应用
agriculture
储存温度
2-8°C
SMILES字符串
OC(=O)CCC(=O)Nc1ccc(Br)cn1
InChI
1S/C9H9BrN2O3/c10-6-1-2-7(11-5-6)12-8(13)3-4-9(14)15/h1-2,5H,3-4H2,(H,14,15)(H,11,12,13)
InChI key
XFYYQDHEDOXWGA-UHFFFAOYSA-N
应用
Bikinin 已被用于:
- 作为拟南芥 Col-0 幼苗中的糖原合酶激酶 3（GSK3）抑制剂，用于测试其对基因表达的影响
- 作为诱导培养基的成分和 GSK3 抑制剂，用于测试其对拟南芥叶盘或子叶中叶肉细胞的影响
- 作为油菜素内酯激动剂，用于测试其对毛柄水毛茛陆地叶指数的影响
生化/生理作用
Bikinin是一种油菜素类固醇（BR）信号转导的强激活剂。它是拟南芥GSK-3抑制剂、拟南芥SHAGGY相关激酶抑制剂、以及GSK-3样激酶BIN2抑制剂。Bikinin可通过干扰ATP结合直接抑制BIN2（II类GSK3s）。 Bikinin对拟南芥GSK3激酶的亚类（包括BIN2和ASKα 、γ 、ε、ι,和θ）具有特异性。
WGK
WGK 3
Bert De Rybel et al.
Chemistry & biology, 16(6), 594-604 (2009-06-25)
Glycogen synthase kinase 3 (GSK3) is a key regulator in signaling pathways in both animals and plants. Three Arabidopsis thaliana GSK3s are shown to be related to brassinosteroid (BR) signaling. In a phenotype-based compound screen we identified bikinin, a small
Structure-function study of a novel inhibitor of the casein kinase 1 family in Arabidopsis thaliana.
Ami N Saito et al.
Plant direct, 3(9), e00172-e00172 (2019-09-25)
Casein kinase 1 (CK1) is an evolutionarily conserved protein kinase family among eukaryotes. Studies in non-plants have shown CK1-dependent divergent biological processes, but the collective knowledge regarding the biological roles of plant CK1 lags far behind other members of the
Yunshuai Huang et al.
Journal of integrative plant biology, 64(10), 1883-1900 (2022-07-30)
Grain size is a key agronomic trait that determines the yield in plants. Regulation of grain size by brassinosteroids (BRs) in rice has been widely reported. However, the relationship between the BR signaling pathway and grain size still requires further
Wei Lin et al.
Science advances, 6(26), eaaz2963-eaaz2963 (2020-07-09)
DNA demethylation is important for the erasure of DNA methylation. The role of DNA demethylation in plant development remains poorly understood. Here, we found extensive DNA demethylation in the CHH context around pericentromeric regions and DNA demethylation in the CG
Jinyu Luo et al.
Plant communications, 3(6), 100419-100419 (2022-08-06)
High temperature adversely affects plant growth and development. The steroid phytohormones brassinosteroids (BRs) are recognized to play important roles in plant heat stress responses and thermotolerance, but the underlying mechanisms remain obscure. Here, we demonstrate that the glycogen synthase kinase
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门