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应用
MEGX has been used in an approach to improve the yield of N-dealkylated lidocaine.
生化/生理作用
Lidocaine metabolite
MEGX is generated by hepatic cytochrome P-450 system upon oxidative de-ethylation. Measurement of MEGX by immunoassay contributes to liver function test. MEGX possesses antiarrhythmic action and therefore extends lidocaine effect.
Monoethylglycinexylidide (MEGX) is an active metabolite of lidocaine.
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Elaine Christine Dantas Moisés et al.
European journal of clinical pharmacology, 64(12), 1189-1196 (2008-08-06)
Peridural blockade with lidocaine, bupivacaine, and fentanyl is an anesthetic procedure extensively used in obstetrics, justifying the pharmacokinetic study of these drugs during labor. To investigate the influence of the physiopathological changes of gestational diabetes mellitus (GDM) on the pharmacokinetics
E J Dickey et al.
Equine veterinary journal, 40(4), 348-352 (2008-02-13)
Continuous-rate infusions (CRI) of lidocaine are often used for prolonged duration but, to date, only limited time/concentration relationships administered as a short term (24 h) CRI have been reported. To determine the time/concentration profile of lidocaine and its active metabolites
Classic Papers in Critical Care, 179-179 (2010)
Georgette Oni et al.
Aesthetic surgery journal, 32(4), 495-503 (2012-03-29)
Topical anesthetics are commonly applied for a variety of indications. Several lidocaine-containing topical anesthetics are available for purchase over the counter (OTC). Recently, the authors' group has shown that there is great interindividual discrepancy in the manner in which lidocaine
Pharmacokinetics of lidocaine and its active metabolite, monoethylglycinexylidide, after intravenous administration of lidocaine to awake and isoflurane-anesthetized cats
Thomasy SM, et al.
American Journal of Veterinary Research, 66(7), 1162-1166 (2005)
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