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Merck
CN

SML0081

Sigma-Aldrich

Zacopride hydrochloride hydrate

≥98% (HPLC)

别名:

4-Amino-N-1-azabicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxybenzamide hydrochloride hydrate

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About This Item

经验公式(希尔记法):
C15H20ClN3O2 · HCl · xH2O
分子量:
346.25 (anhydrous basis)
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

质量水平

检测方案

≥98% (HPLC)

形式

powder

储存条件

desiccated

颜色

white to tan

溶解性

H2O: ≥10 mg/mL

创始人

Wyeth

储存温度

2-8°C

SMILES字符串

O.Cl.COc1cc(N)c(Cl)cc1C(=O)NC2CN3CC[C@H]2CC3

InChI

1S/C15H20ClN3O2.ClH.H2O/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19;;/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20);1H;1H2

InChI key

NPXXKMBXEODDAF-UHFFFAOYSA-N

生化/生理作用

Zacopride is a sub-nanomolar antagonist of the serotonin 5-HT3 receptor that also displays agonist-like activity against 5-HT4 receptors. It is a potent anxiolytic in animal models, and also has strong antiemetic effects, and also increases aldosterone levels via activation of 5-HT4 receptor in the adrenal glands.

特点和优势

This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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