质量水平
检测方案
≥98% (HPLC)
形式
powder
旋光性
[α]/D 75 to 95°, c = 1 in methanol
颜色
white to beige
溶解性
DMSO: ≥13 mg/mL
储存温度
room temp
SMILES字符串
COc1cc2C[C@H](C)[C@@](C)(O)Cc3cc(OC)c(OC)c(OC)c3-c2c(OC)c1OC
InChI
1S/C24H32O7/c1-13-9-14-10-16(26-3)20(28-5)22(30-7)18(14)19-15(12-24(13,2)25)11-17(27-4)21(29-6)23(19)31-8/h10-11,13,25H,9,12H2,1-8H3/t13-,24-/m0/s1
InChI key
YEFOAORQXAOVJQ-RZFZLAGVSA-N
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应用
五味子甲素可用于氧化应激相关的细胞信号传导研究。
生化/生理作用
五味子甲素是一种天然产物,具有抗氧化和抗炎作用。减少 ROS 的形成,抑制线粒体途径的凋亡过程和氧化应激。据报道,五味子甲素具有保肝、抗肿瘤、抗病毒、抗遗忘作用,对谷氨酸引起的神经毒性具有神经保护活性。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Journal of the science of food and agriculture, 91(4), 694-702 (2011-02-09)
Schisandra chinensis, commonly used in Asia for tea material and traditional Chinese medicine, is presumed to enhance mental and intellectual functions. In this study, the effects and signalling mechanisms of a purified compound schisandrin, one of the lignan of Schisandra
Immunology letters, 139(1-2), 93-101 (2011-06-08)
The lipopolysaccharide (LPS) of Porphyromonas gingivalis is thought to induce periodontitis. In this study, we isolated Schisandrin from the dried fruits of Schisandra chinensis and examined the anti-inflammatory effect of Schisandrin in macrophages stimulated with LPS from P. gingivalis. First
Lipids in health and disease, 11, 120-120 (2012-09-20)
Schisandra, a globally distributed plant, has been widely applied to health care products. Here, we investigated the effects of dietary intake of Fructus Schisandrae chinensis (FSC), both aqueous and ethanolic extracts (AqFSC, EtFSC), on serum/hepatic lipid contents in normal diet
Drug development and industrial pharmacy, 36(11), 1356-1363 (2010-09-21)
Wurenchun is the alcohol extract from Fructus Schisandrae Chinensis, which has good efficiency in lowering abnormal serum glutamic pyruvic transaminase (SGPT) level of patients suffering from acute or chronic hepatitis. The main purpose of this work is to prepare self-emulsifying
Molecules (Basel, Switzerland), 16(5), 3713-3722 (2011-05-05)
Lignans are imporant active ingredients of Schisandra sphenanthera. A micellar electrokinetic chromatography method was developed for the simultaneous determination of eight lignans--schizandrin, schisandrol B, schisantherin A, schisanhenol, anwulignan, deoxyschizandrin, schizandrin B and schizandrin C--in different parts of S. sphenanthera. The
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