所有图片(1)
About This Item
经验公式（希尔记法）:
C26H22O10 · xH2O
CAS号:
分子量:
494.45 (anhydrous basis)
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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方案
≥98% (HPLC)
表单
powder
颜色
yellow
溶解性
H2O: ≥19 mg/mL
运输
wet ice
储存温度
−20°C
SMILES字符串
O.OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2\C=C\c3ccc(O)c(O)c3
InChI
1S/C26H22O10.H2O/c27-18-7-2-14(11-21(18)30)1-6-17-16(4-9-20(29)25(17)33)5-10-24(32)36-23(26(34)35)13-15-3-8-19(28)22(31)12-15;/h1-12,23,27-31,33H,13H2,(H,34,35);1H2/b6-1+,10-5+;/t23-;/m1./s1
InChI key
XFUSRNNWIRPEDG-FYLUTCCGSA-N
应用
丹酚酸 A 水合物可用于细胞信号传导研究。
丹酚酸 A 水合物已被用作迷迭香酸衍生物，用于抑制人细胞系中的 DNA 聚合酶 e。
丹酚酸 A 水合物已被用作迷迭香酸衍生物，用于抑制人细胞系中的 DNA 聚合酶 e。
生化/生理作用
丹酚酸 A 作为活性氧的清除剂，减少白细胞对内皮细胞的粘附，抑制基质金属蛋白酶和炎症。它具有心脏保护作用，因为它抑制细胞凋亡，减少受损心脏组织中的脂质过氧化，并减少乳酸脱氢酶的泄漏。
丹酚酸 A 是最初从丹参中分离得到的具有细胞保护作用的抗氧化剂。研究发现它能减弱 PDGF 诱导的肝星状细胞 ROS 的形成，对异丙肾上腺素诱导的大鼠心肌损伤有保护作用。
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Huaying Fan et al.
Evidence-based complementary and alternative medicine : eCAM, 2012, 508938-508938 (2011-07-27)
Salvianolic acid A (SAA), one of the major active components of Danshen that is a traditional Chinese medicine, has been reported to possess protective effect in cardiac diseases and antioxidative activity. This study aims to investigate the cardioprotection of SAA
Jing Wang et al.
Folia neuropathologica, 59(1), 50-66 (2021-05-11)
More than 50 million people are affected by traumatic brain injury (TBI) each year around the world, and nearly half of the population worldwide will have one or more TBI(s) in their lifetime. And in 2017, more than 1.39 billion
Shou-Bao Wang et al.
Journal of Asian natural products research, 14(11), 1084-1092 (2012-10-31)
Epoxyeicosatrienoic acids (EETs) and their regulating enzyme soluble epoxide hydrolase (sEH) have been associated with ischemic stroke. Salvianolic acid A (SAA) is proved to display potent cerebroprotection. However, little information is available about the link between them. This study aimed
Kwang-Seok Oh et al.
International immunopharmacology, 11(11), 1901-1906 (2011-08-16)
Salvianolic acid A, an active compound present in Salvia miltiorrhiza, is a phenolic carboxylic acid derivative, ((2R)-3-(3,4-Dihydroxyphenyl)-2-[(E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl) ethenyl]-3,4-dihydroxyphenyl] prop-2-enoyl]oxypropanoic acid). The present study was performed to investigate the underlying mechanisms of anti-inflammatory effects with salvianolic acid A, specially focused on
Huanjun Pan et al.
Journal of cardiovascular pharmacology, 58(5), 535-542 (2011-07-29)
Salvianolic acid A (Sal A), the water-soluble component from the root of the Salvia miltiorrhiza plant, possesses antioxidant, antiproliferative, and antiplatelet properties. However, whether it plays a role in the protection against ischemia-reperfusion (I/R) injury in rat hearts has yet
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