推荐产品
应用
CCG-63802 may be used to study G-protein-mediated cell signaling.
生化/生理作用
CCG-63802 is a reversible, allosteric inhibitor of RGS4
GCC-63802 binds to RGS4 and blocks interaction with Goa (IC50 = 1.9 uM). RGS4 (Regulator of G protein Signaling) is one of the RGP proteins responsible for terminating mu opioid receptor signaling. RSG proteins are GTPase activators, and drive G protein subunits to an inactive, GDP-bound form.
特点和优势
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the G Proteins (Heterotrimeric) and Opioid Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
商品
由α，β和γ亚基所组成的异源三聚体G蛋白通过调节细胞内效应蛋白如酶和离子通道，可对由活化的七跨膜（7TM）受体产生的细胞外信号产生响应。
Heterotrimeric G proteins modulate intracellular signals from 7TM receptors, impacting various cellular functions and drug targets.
我们可提供多种与阿片受体相关的产品，以满足您的各类研究需求。
We offers many products related to opioid receptors for your research needs.
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