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Merck
CN

SMB01073

Sigma-Aldrich

Eurycomanone

≥90% (LC/MS-ELSD)

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别名:
Pasakbumin A
经验公式(希尔记法):
C20H24O9
CAS号:
分子量:
408.40
MDL编号:
UNSPSC代码:
12352205
NACRES:
NA.25

生物来源

plant

检测方案

≥90% (LC/MS-ELSD)

形式

solid

分子量

408.4

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

−20°C

InChI

1S/C20H24O9/c1-7-4-10(21)13(23)17(3)9(7)5-11-18-6-28-20(27,16(17)18)12(22)8(2)19(18,26)14(24)15(25)29-11/h4,9,11-14,16,22-24,26-27H,2,5-6H2,1,3H3/t9-,11+,12+,13+,14-,16+,17+,18+,19-,20-/m0/s1

InChI key

UCUWZJWAQQRCOR-OKNZMGBLSA-N

一般描述

Eurycomanone, also known as Pasakbumin A, is a bioactive quassinoid natural compound commonly derived from Eurycoma longifolia (Tongkat Ali). Current research indicates that this plant metabolite is an inhibitor and may possess diverse biological activities, including antitumor, antimalarial, and anticancer properties.

应用

Eurycomanone is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

生化/生理作用

Eurycomanone inhibited Jurkat and K562 leukemia cells viability and proliferation without affecting healthy cells and enhanced testosterone steroidogenesis.

特点和优势

  • Suitable for Biochemical and Biomedical research
  • Versatile and adaptable for wide variety of laboratory and research applications

其他说明

For additional information on our range of Biochemicals, please complete this form.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Shéhérazade Hajjouli et al.
Molecules (Basel, Switzerland), 19(9), 14649-14666 (2014-09-18)
Eurycomanone and eurycomanol are two quassinoids from the roots of Eurycoma longifolia Jack. The aim of this study was to assess the bioactivity of these compounds in Jurkat and K562 human leukemia cell models compared to peripheral blood mononuclear cells
Bin-Seng Low et al.
Journal of ethnopharmacology, 149(1), 201-207 (2013-07-03)
Eurycoma longifolia Jack (Simaroubaceae family), known locally as 'Tongkat Ali' by the ethnic population, is popularly taken as a traditional remedy to improve the male libido, sexual prowess and fertility. Presently, many tea, coffee and carbonated beverages, pre-mixed with the

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