所有图片(1)
别名:
4-O-(beta-D-apiofuranosyl(1-2)-beta-D-glucopyranosyl)isoliquiritigenin, Isoliquiritigenin-4′-O-apiosyl(1→2)glucoside, Isoliquiritin apioside
经验公式（希尔记法）:
C26H30O13
推荐产品
生物来源
plant
检测方案
≥85% (LC/MS-ELSD)
形式
solid
分子量
550.51
溶解性
water: slightly soluble
应用
metabolomics
vitamins, nutraceuticals, and natural products
储存温度
−20°C
InChI
1S/C26H30O13/c27-10-19-20(32)21(33)22(39-25-23(34)26(35,11-28)12-36-25)24(38-19)37-15-5-1-13(2-6-15)3-8-17(30)16-7-4-14(29)9-18(16)31/h1-9,19-25,27-29,31-35H,10-12H2/b8-3+/t19-,20-,21+,22-,23+,24-,25+,26-/m1/s1
InChI key
VMMVZVPAYFZNBM-KVFWHIKKSA-N
一般描述
Neolicuroside, also known as Isoliquiritin apioside, is a chalcone glycoside structurally related to steroidal saponins. This bioactive plant metabolite is commonly derived from the roots of Glycyrrhiza Sp. plants and has demonstrated anti-inflammatory, anti-tussive, anti-tumor, antigenotoxic(1), anti-diabetic, and antioxidant properties.
Natural product derived from plant source.
应用
It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.
生化/生理作用
Neolicuroside modulates signaling pathways (e.g., MAPK, NF-κB), impacting vital cell processes such as proliferation, differentiation, and apoptosis. Its multitargeted mechanism includes scavenging free radicals, suppressing pro-inflammatory cytokine production, inhibiting matrix metalloproteinase (MMP) activity and hindering cancer cell growth through apoptosis and cell cycle arrest. Furthermore, it also exerts immunomodulatory effects possibly by activating toll-like receptor 4 (TLR4).
特点和优势
- High quality compound suitable for multiple research applications
- Compatible with HPLC and mass spectrometry techniques
其他说明
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WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Evaluation of antigenotoxic activity of isoliquiritin apioside from Glycyrrhiza glabra L
Kaur P, et al.
Toxicology in vitro, 23, 680-686 (2009)
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