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Merck
CN

SMB01042

Sigma-Aldrich

Allocryptopin

≥90% (LC/MS-ELSD)

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别名:
β-Allocryptopine, γ-Homochelidonine, Fagarine I
经验公式(希尔记法):
C21H23NO5
CAS号:
分子量:
369.41
MDL编号:
UNSPSC代码:
12352205
NACRES:
NA.25

生物来源

plant

检测方案

≥90% (LC/MS-ELSD)

形式

solid

分子量

369.41

溶解性

water: slightly soluble

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

−20°C

InChI

1S/C21H23NO5/c1-22-7-6-14-9-19-20(27-12-26-19)10-15(14)17(23)8-13-4-5-18(24-2)21(25-3)16(13)11-22/h4-5,9-10H,6-8,11-12H2,1-3H3

InChI key

HYBRYAPKQCZIAE-UHFFFAOYSA-N

一般描述

Allocryptopin, an isoquinoline alkaliod, is a natural product commonly available from Allocryptopinus japonicus, Glaucium arabicum, Zanthoxylum beecheyanum, Berberis integerrima, and Macleaya cordata. This secondary metabolite derived from plant sources exhibits various biological activities such as anti-inflammatory, antiviral, and antitumor properties.

应用

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

生化/生理作用

Allocryptopine has been reported to possess strong antibacterial, anti-inflammatoty, antiparasitic, antineoplastic and anti-addictive activities. Allocryptopine inhibits human acetylcholinesterase and butyrylcholinesterase. It blocks hERG current in HEK293 cells. Allocryptopine strongly enhanced the I(peak) of the T353I channel by enhancing the plasma membrane (PM) expression of Nav1.5 and rescued defective trafficking after co-incubation with HEK293 cells that carry mutation channel 24 h.

特点和优势

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

其他说明

For additional information on our range of Biochemicals, please complete this form.

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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