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Merck
CN

SMB01039

Sigma-Aldrich

Murrayafoline A

≥90% (LC/MS-ELSD)

别名:

1-Methoxy-3-methyl-9H-carbazole

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About This Item

经验公式(希尔记法):
C14H13NO
CAS号:
分子量:
211.26
MDL编号:
UNSPSC代码:
12352205
NACRES:
NA.25

生物来源

plant

检测方案

≥90% (LC/MS-ELSD)

形式

solid

分子量

211.26

溶解性

water: slightly soluble

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

−20°C

InChI

1S/C14H13NO/c1-9-7-11-10-5-3-4-6-12(10)15-14(11)13(8-9)16-2/h3-8,15H,1-2H3

InChI key

HDETUOZJFUNSKG-UHFFFAOYSA-N

一般描述

Murrayafoline A, a carbazole alkaloid, is a bioactive natural compound commonly derived from plants such as Murraya euchrestifolia, Murraya kwangsiensis, Clausena excavata, Clausena dunniana, and Glycosmis stenocarpa. Current research indicates that this plant metabolite is an inhibitor and may possess diverse biological activities, including anticancer, antimalarial, cardioprotective and antifungal properties.

应用

Murrayafoline A is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

生化/生理作用

Murrayafoline A may be a potential chemotherapeutic agent for use in the treatment of colon cancer and may be useful in preventing the progression of vascular complications such as restenosis.

特点和优势

  • Suitable for Biochemical and Biomedical research
  • Versatile and adaptable for wide variety of laboratory and research applications

其他说明

For additional information on our range of Biochemicals, please complete this form.

象形图

Health hazard

警示用语:

Warning

危险声明

危险分类

Aquatic Chronic 4 - Carc. 2 - Muta. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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访问文档库

Joo-Hui Han et al.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 19(5), 421-426 (2015-09-04)
The increased potential for vascular smooth muscle cell (VSMC) growth is a key abnormality in the development of atherosclerosis and post-angioplasty restenosis. Abnormally high activity of platelet-derived growth factor (PDGF) is believed to play a central role in the etiology
Hyuk Choi et al.
Biochemical and biophysical research communications, 391(1), 915-920 (2009-12-08)
Molecular lesions in Wnt/beta-catenin signaling and subsequent up-regulation of beta-catenin response transcription (CRT) occur frequently during the development of colon cancer. To identify small molecules that suppress CRT, we screened natural compounds in a cell-based assay for detection of TOPFalsh

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