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Merck
CN

SMB01030

Sigma-Aldrich

Theviridoside

≥90% (LC/MS-ELSD)

别名:

Methyl (1S,4aR,7aR)-1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-4a-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylate (ACI), Theveridoside, Theveside methyl ester

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About This Item

经验公式(希尔记法):
C17H24O11
CAS号:
分子量:
404.37
MDL编号:
UNSPSC代码:
12352205
NACRES:
NA.25

生物来源

plant

方案

≥90% (LC/MS-ELSD)

表单

solid

分子量

404.37

溶解性

water: soluble

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

−20°C

SMILES字符串

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@@H]2OC=C([C@@]3([C@H]2C(=CC3)CO)O)C(=O)OC

InChI

1S/C17H24O11/c1-25-14(23)8-6-26-15(10-7(4-18)2-3-17(8,10)24)28-16-13(22)12(21)11(20)9(5-19)27-16/h2,6,9-13,15-16,18-22,24H,3-5H2,1H3/t9-,10+,11-,12+,13-,15+,16+,17+/m1/s1

InChI key

LDBMLOLBWUOZGG-DOFVRBEMSA-N

一般描述

Theviridoside, an iridoid glycoside, is a natural product commonly found in plants of Cerbera odollam, Lippia javanica, Lippia turbinata and Thevetia neriifolia. In Cancer research, it exerts a significant effect on cell function and signal transduction, inducing cell cycle arrest and apoptosis in cancer cells while inhibiting the production of pro-inflammatory cytokines. This compound exhibits potent biological activity, including anti-cancer, antifungal, anti-inflammatory, and anti-viral activities.

应用

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

生化/生理作用

Theviridoside acts by inhibiting the Na+/K+-ATPase pump, leading to increased intracellular calcium levels and the activation of multiple signaling pathways.

特点和优势

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

其他说明

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Frédéric Martin et al.
Phytochemistry, 68(9), 1307-1311 (2007-03-27)
Sixteen crude extracts from six Panamanian plants of the family Bignoniaceae were submitted to rapid TLC tests against DPPH and acetylcholinesterase. Pithecoctenium crucigerum (L.) A.H. Gentry, which showed interesting activity against DPPH, has been studied. The chemical investigation of the

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