SMB00706
番茄红素
≥98% (HPLC), from tomato
别名:
ψ,ψ-胡萝卜素, 2,6,10,14,19,23,27,31-八甲基-三十二烷-2,6,8,10,12,14,16,18,20,22,24,26,30-十三烯
InChI
1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21+,36-22+,37-27+,38-28+,39-29+,40-30+
SMILES string
C\C(C)=C\CC\C(C)=C\C=C\C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C=C(/C)CC\C=C(\C)C
InChI key
OAIJSZIZWZSQBC-GYZMGTAESA-N
biological source
tomato
assay
≥98% (HPLC)
form
powder
mol wt
536.87
storage condition
protect from light
solubility
THF: 1 mg/mL, chloroform: 5 mg/mL
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
shipped in
dry ice
storage temp.
−20°C
Quality Level
正在寻找类似产品? 访问 产品对比指南
General description
番茄红素是一种无环类胡萝卜素色素，是一种具有生物活性的天然化合物，通常由西瓜、粉红番石榴、番茄等红色水果和蔬菜以及光合藻类产生。目前研究表明，这种植物代谢物是一种抑制剂，可能具有多种生物活性，包括抗氧化、抑制癌症、辐射防护、抗癌和抗炎特性。
Application
番茄红素已用于：
- 分析其对体外小鼠表皮细胞系皮肤肿瘤的化学预防作用
- 作为高效液相色谱(HPLC)定量的参考标准品，分析哺乳动物细胞系中内源性类胡萝卜素的抗氧化能力
- 作为高效液相色谱(HPLC)的参考标准品，鉴定酿酒酵母工程菌中的类胡萝卜素
番茄红素是从植物中提取的天然产物，可用于化合物筛选库、代谢组学、植物化学和药物开发研究。
Biochem/physiol Actions
已发现番茄红素具有抗口腔癌活性，并且可以通过下调NOX4而抑制人肝腺癌细胞的转移。番茄红素还被发现是心血管疾病患者的有益补充剂。
西红柿中的抗氧化剂微量营养素，与降低癌症和心血管疾病风险有关。通过间隙连接蛋白 43 的表达上调促进细胞间间隙连接通讯以及抑制培养中癌细胞增殖。抑制胆固醇合成以及促进低密度脂蛋白降解。
Features and Benefits
- 适用于多种研究应用的优质化合物
- 兼容HPLC 和质谱技术
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Lycopene: potent antioxidant for oral premalignancy and oral cancer
Sonunu, S.; et al.
European Journal of Biomedical AND Pharmaceutical sciences, 2, 135-144 (2015)
A V Rao et al.
Journal of the American College of Nutrition, 19(5), 563-569 (2000-10-07)
Lycopene, a carotenoid without provitamin-A activity, is present in many fruits and vegetables; however, tomatoes and processed tomato products constitute the major source of lycopene in North American diet. Among the carotenoids, lycopene is a major component found in the
Sonia Gupta et al.
International journal of preventive medicine, 6, 70-70 (2015-09-04)
Without pigments, we are nothing. Life presents us with a kaleidoscope of colors. From the green grass of home to a forest's ruddy autumn hues, we are surrounded by living colors. Living things obtain their colors, with few exceptions, from
High-level beta-carotene production from xylose by engineered Saccharomyces cerevisiae without overexpression of a truncated HMG1 (tHMG1)
Sun L, et al.,
Biotechnology and Bioengineering, 3522-3532 (2020)
Bo-Yi Jhou et al.
Journal of agricultural and food chemistry, 65(32), 6893-6903 (2017-07-21)
NADPH oxidase 4 (NOX4), with the sole function to produce reactive oxygen species (ROS), can be a molecular target for disrupting cancer metastasis. Several studies have indicated that lycopene exhibited anti-metastatic actions in vitro and in vivo. However, the role
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持