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Merck
CN

SMB00705

Sigma-Aldrich

芝麻素

≥98% (HPLC)

别名:

崖椒醇

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About This Item

经验公式(希尔记法):
C20H18O6
CAS号:
分子量:
354.35
MDL编号:
UNSPSC代码:
12352205
NACRES:
NA.25

质量水平

检测方案

≥98% (HPLC)

形式

powder

溶解性

DMSO: 10 mg/mL

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

−20°C

SMILES字符串

C1Oc2ccc(cc2O1)[C@H]3OC[C@H]4[C@@H]3CO[C@@H]4c5ccc6OCOc6c5

InChI

1S/C20H18O6/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19+,20+/m0/s1

InChI key

PEYUIKBAABKQKQ-AFHBHXEDSA-N

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一般描述

芝麻素是从芝麻或芝麻籽和芝麻油中提取的最丰富的木脂素。

应用

芝麻素已用作参考标准品以研究芝麻中细胞色素P450酶芝麻素合酶在将松香素转化为芝麻素的活性。

生化/生理作用

芝麻素具有多种健康益处,包括降胆固醇、降压、抗癌、抗衰老、免疫调节、降血糖、抗血栓、保肝和抗氧化活性等。它还被证明可以与维生素E协同抗脂质过氧化。研究发现,芝麻素在肝脏中被代谢成几种儿茶酚形式。这些儿茶酚具有很强的清除超氧自由基的能力。
非竞争性δ 5-去饱和酶抑制剂。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Mitsuo Namiki
Critical reviews in food science and nutrition, 47(7), 651-673 (2007-10-19)
The results of recent food chemical and nutraceutical studies on the traditionally well-known health value of sesame are described, including some aspects of the utilization of sesame. The highly antioxidative activity of sesame oil was clarified and found to involve
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Sarah Dalibalta et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 28(10), 1276-1289 (2020-11-03)
Sesamin, a major lignin isolated from sesame (Sesamum indicum) seeds and sesame oil, is known to possess antioxidant and anti-inflammatory properties. Several studies have revealed that oxidative stress and inflammation play a major role in a variety of cardiovascular diseases
Yun-Ping Lim et al.
Evidence-based complementary and alternative medicine : eCAM, 2012, 242810-242810 (2012-05-31)
Inconsistent expression and regulation of drug-metabolizing enzymes (DMEs) are common causes of adverse drug effects in some drugs with a narrow therapeutic index (TI). An important cytochrome, cytochrome P450 3A4 (CYP3A4), is predominantly regulated by a nuclear receptor, pregnane X
W C Johnson et al.
Life sciences, 51(15), 1229-1236 (1992-01-01)
A two step fractionation of conditioned media made from the darkly pigmented dorsal skin of the channel catfish, Ictalurus punctatus, has produced fractions that contain a melanization stimulating factor (MSF). Isolated neural tubes of Xenopus laevis embryos exposed to conditioned

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