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Merck
CN

SMB00701

Sigma-Aldrich

芝麻林素

≥97%, from Sesamum indicum (sesame)

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别名:
5-[(1S,3aR,4R,6aR)-4-(1,3- 苯并二唑-5-烷氧基)四羟基-1H,3H-furo[3,4-c]呋喃-1-基]-1,3-苯并二恶唑
经验公式(希尔记法):
C20H18O7
CAS号:
分子量:
370.35
UNSPSC代码:
12352205
NACRES:
NA.25

生物来源

Sesamum indicum (sesame)

质量水平

检测方案

≥97%

形式

powder

溶解性

DMSO: 10 mg/mL

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

−20°C

SMILES字符串

[H][C@@]12[C@@H](C(C=C3)=CC4=C3OCO4)OC[C@]1([H])[C@@H](OC5=CC6=C(C=C5)OCO6)OC2

InChI

1S/C20H18O7/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)27-12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19+,20+/m0/s1

InChI key

ZZMNWJVJUKMZJY-AFHBHXEDSA-N

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一般描述

芝麻素是从芝麻中提取的呋喃木脂素。它在水中的溶解度很小。芝麻素的化学结构包括两种苯丙素,它们的丙基侧连接到中心碳上。在许多其他芝麻品种中也有报道。

生化/生理作用

它还具有抗菌、抗黑色素生成和神经保护作用。
据报道,芝麻素具有有益的生理特性,如抗氧化、抗突变、抗衰老和抗炎活性。 对大鼠肝、肾的脂质过氧化也有抑制作用。芝麻素通过增加Burkitts淋巴瘤细胞上NKG2D配体的表达,增强NK细胞的裂解活性,在癌症治疗中具有潜在的免疫治疗价值。 此外,研究表明,芝麻素可抑制β-分泌酶,通过日常食用对预防痴呆具有重要作用。

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

危险分类

Skin Sens. 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Afaf Kamal-Eldin et al.
Recent patents on food, nutrition & agriculture, 3(1), 17-29 (2010-12-01)
Sesame seed contains very high levels (up to 2.5%) of furofuran lignans with beneficial physiological activities, mainly sesamin, sesamolin, and sesaminol glucosides. Reported activities of sesame seed lignans include inter alias modulation of fatty acid metabolism, inhibition of cholesterol absorption
T Lind et al.
Acta orthopaedica Belgica, 58(1), 81-83 (1992-01-01)
The intra-articular pressures in the glenohumeral joint in different positions were measured in 12 cadaveric shoulders. The lowest pressure was found in abduction combined with traction. A significant rise in pressure was seen in positions combining flexion or abduction with
M H Kang et al.
The Journal of nutrition, 128(6), 1018-1022 (1998-06-18)
Although the sesame lignans, sesaminol and sesamolinol, have been shown to possess antioxidative activity, less is known about the metabolism and antioxidative properties of sesamolin, a major constituent of sesame oil. To determine the ability of sesamolin to act as
Reny Rosalina et al.
Molecules (Basel, Switzerland), 26(19) (2021-10-14)
Sesame seeds are rich in lignan content and have been well-known for their health benefits. Unlike the other sesame lignan compounds (i.e., sesamin and sesamol), the study of the pharmacological activity of sesamolin has not been explored widely. This review
Jeong Hwa Kim et al.
International immunopharmacology, 28(2), 977-984 (2015-08-25)
Sesamolin and sesamin are representative lignans found in sesame seed. The present study was designed to demonstrate the anti-cancer activity of sesamolin achieved by increasing the expression level of NKG2D ligands on Raji cells, which are derived from Burkitt's lymphoma.

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