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Merck
CN

SMB00605

Sigma-Aldrich

头孢匹林钠

别名:

头孢匹林钠 钠盐, 3-[(乙酰氧基)甲基]-8-氧代-7-{(4-吡啶巯基)乙酰基]氨基}-5-硫-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸 单钠盐, 头孢吡硫钠

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About This Item

经验公式(希尔记法):
C17H16N3NaO6S2
CAS号:
分子量:
445.45
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:

表单

powder

储存条件

(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

作用机制

cell wall synthesis | interferes

储存温度

2-8°C

SMILES字符串

[Na+].CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)CSc3ccncc3)C2=O)C([O-])=O

InChI

1S/C17H17N3O6S2.Na/c1-9(21)26-6-10-7-28-16-13(15(23)20(16)14(10)17(24)25)19-12(22)8-27-11-2-4-18-5-3-11;/h2-5,13,16H,6-8H2,1H3,(H,19,22)(H,24,25);/q;+1/p-1/t13-,16-;/m1./s1

InChI key

VGEOUKPOQQEQSX-OALZAMAHSA-M

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生化/生理作用

Cephapirin is a cephalosporin C antibiotic effective against Gram-positive and Gram-negative bacteria including Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia and Proteus mirabilis.

包装

25MG

制备说明

Cephapirin is soluble in H2O up to approximately 50 mg/mL and slightly soluble in DMSO and MeOH up to approximately 1 mg/mL.

其他说明

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

象形图

Health hazardExclamation mark

警示用语:

Danger

危险分类

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

13 - Non Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Laboratory studies with a new cephalosporanic acid derivative.
D R Chisholm et al.
Antimicrobial agents and chemotherapy, 9, 244-246 (1969-01-01)
J Axelrod et al.
Applied microbiology, 22(5), 904-908 (1971-11-01)
Cephapirin, a new semisynthetic cephalosporin derivative, was found to have an antibacterial spectrum similar to that of cephalothin. Staphylococcus aureus was inhibited by cephapirin concentrations of 0.09 to 12.5 mug/ml. S. epidermidis, S. viridans, S. pyogenes, and Diplococcus pneumonia isolates
J L Bran et al.
Antimicrobial agents and chemotherapy, 1(1), 35-40 (1972-01-01)
Cephapirin sodium, a cephalosporin for parenteral use, was evaluated in vitro and in 27 patients. Cephapirin had activity equivalent to cephalothin against 25 strains each of Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Staphylococcus aureus; 10 strains each of Diplococcus

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