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Merck
CN
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文件

安全信息

SMB00451

Sigma-Aldrich

酸枣仁皂苷B

≥98% (HPLC)

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别名:
Jujubopside B
经验公式（希尔记法）:
C52H84O21
CAS号:
55466-05-2
分子量:
1045.21
MDL编号:
MFCD03427710
UNSPSC代码:
12352205
PubChem化学物质编号:
329825020
NACRES:
NA.25

生物来源

plant (Semen Ziziphus spinosa)

检测方案

≥98% (HPLC)

形式

powder

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

2-8°C

SMILES字符串

C[C@@]12[C@](CC[C@]3(C)[C@]2([H])CC[C@@]4([H])[C@@]3(CO5)C[C@@]65[C@]4([H])[C@@](C)(O)C[C@H](C=C(C)C)O6)([H])C(C)(C)[C@@H](O[C@]7([H])OC[C@H](O)[C@H](O[C@]8([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O[C@@]9([H])[C@H](O)[C@@H](O)[C@H](O)CO9)[C@H]7O[C@@]%10([H])

InChI

1S/C52H84O21/c1-22(2)15-24-16-50(8,63)42-25-9-10-30-48(6)13-12-31(47(4,5)29(48)11-14-49(30,7)51(25)20-52(42,73-24)66-21-51)69-45-41(72-44-38(62)35(59)32(56)23(3)67-44)39(27(55)19-65-45)70-46-40(36(60)34(58)28(17-53)68-46)71-43-37(61)33(57)26(54)18-64-43/h15,23-46,53-63H,9-14,16-21H2,1-8H3/t23-,24-,25+,26+,27-,28+,29-,30+,31-,32-,33-,34+,35+,36-,37+,38+,39-,40+,41+,42-,43-,44-,45-,46-,48-,49+,50-,51-,52-/m0/s1

InChI key

OAVAUZCEOWCYCC-QEOGCQCLSA-N

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一般描述

Jujuboside B (JuB) is a saponin isolated from Semen Ziziphus spinosa (SZS) used in Traditional Chinese Medicine.

生化/生理作用

Jujuboside B is known for its treatment of insomnia and anxiety and has been reported to have activities relevant to the cardiovascular system. Jujuboside B inhibits platelet aggregation and is considered as a preventive drug for platelet-based cardiovascular diseases.
Jujuboside B as food supplement, has neurobeneficial effects and could be a potential drug candidate for treating neurodegenerative diseases.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302

预防措施声明

P301 + P312 + P330

危险分类

Acute Tox. 4 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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访问文档库

Herbal medicine for anxiety, depression and insomnia.
Liu L, et al.
Current Neuropharmacology, 13(4), 481-493 (2015)
Hypnotic effect of jujubosides from Semen Ziziphi Spinosae.
Cao J X, et al.
Journal of Ethnopharmacology, 130(1), 163-166 (2010)
Zizyphus jujuba and its active component jujuboside B inhibit platelet aggregation.
Seo E J, et al.
Phytotherapy Research, 27(6), 829-834 (2013)
Ziziphus spinosa seeds for insomnia: a review of chemistry and psychopharmacology.
Shergis J L, et al.
Phytomedicine, 34, 38-43 (2017)
A Review of Dietary Ziziphus jujuba Fruit (Jujube): Developing Health Food Supplements for Brain Protection.
Chen J, et al.
Evidence-Based Complementary and Alternative Medicine : ECAM, 2017, 10-10 (2017)
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