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Merck
CN

SMB00398

Sigma-Aldrich

Cornin

≥98% (HPLC)

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别名:
Verbenalin, Verbenaloside
经验公式(希尔记法):
C17H24O10
CAS号:
分子量:
388.37
Beilstein:
57895
MDL编号:
UNSPSC代码:
12352205
PubChem化学物质编号:
NACRES:
NA.25

检测方案

≥98% (HPLC)

形式

powder

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

2-8°C

SMILES字符串

[H][C@@]12[C@@H](C)CC(=O)[C@]1([H])C(=CO[C@H]2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C(=O)OC

InChI

1S/C17H24O10/c1-6-3-8(19)11-7(15(23)24-2)5-25-16(10(6)11)27-17-14(22)13(21)12(20)9(4-18)26-17/h5-6,9-14,16-18,20-22H,3-4H2,1-2H3/t6-,9+,10+,11-,12+,13-,14+,16-,17-/m0/s1

InChI key

HLXRWTJXGMHOFN-XJSNKYLASA-N

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一般描述

Cornin is an iridoid glycoside herb. It is obtained from the fruit of Verbena Officinalis L.

生化/生理作用

Cornin is used in cardiology due to its cardioprotective property. It helps to lower blood pressure, improve heart activity, and reverse cardiac hypertrophy It can prevent lipid peroxidation catalyzed by Fe2+. Cornin can also prevent the activities of cyclooxygenase 1 (COX-1) and cyclooxygenase 1 (COX-2) enzymes. It plays a protective role against cerebral ischemia injury.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Zechun Kang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 58, 340-346 (2013-05-25)
In the present study, we sought to elucidate whether Cornin contributes to induce angiogenesis and its mechanisms. To this end, we examined the role of Cornin on human brain microvascular endothelial cell line (HBMEC) proliferation, invasion, and tube formation in
Qun Zhang et al.
BMC complementary medicine and therapies, 21(1), 138-138 (2021-05-11)
Cornin is a commonly used herb in cardiology for its cardioprotective effect. The effect of herbs on the activity of cytochrome P450 enzymes (CYP450s) can induce adverse drug-drug interaction even treatment failure. Therefore, it is necessary to investigate the effect

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