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Merck
CN

SMB00350

Sigma-Aldrich

Dehydroandrographolide

≥98% (HPLC)

别名:

(1R-(1a,2a,4aa,5β(E),8aβ))-3-[2-(Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl)ethylidene)-2(3H)-furanone

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About This Item

经验公式(希尔记法):
C20H28O4
分子量:
332.43
UNSPSC代码:
12352200
PubChem化学物质编号:

生物来源

plant (Andrographis paniculata)

方案

≥98% (HPLC)

表单

powder

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

−20°C

SMILES字符串

OC[C@@]([C@H](O)CC1)(C)C([C@]1(C)[C@H]2C/C=C3C=COC\3=O)CCC2=C

InChI

1S/C20H28O4/c1-13-4-7-16-19(2,10-8-17(22)20(16,3)12-21)15(13)6-5-14-9-11-24-18(14)23/h5,9,11,15-17,21-22H,1,4,6-8,10,12H2,2-3H3/b14-5+/t15-,16?,17+,19-,20-/m0/s1

InChI key

YIIRVUDGRKEWBV-GJVBFGQCSA-N

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一般描述

Dehydroandrographolide is a natural diterpenoid found in Andrographis paniculata.

生化/生理作用

Dehydroandrographolide possesses activity against hepatitis B virus DNA replication.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Naturally derived anti-hepatitis B virus agents and their mechanism of action
Wu Y H.
World Journal of Gastroenterology, 22(1), 188-188 (2016)
Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents.
Chen H, et al.
Bioorganic & Medicinal Chemistry Letters, 24(10), 2353-2359 (2014)
Dehydroandrographolide enhances innate immunity of intestinal tract through up-regulation the expression of hBD-2
Xiong W B, et al.
DARU Journal of Pharmaceutical Sciences, 23(1), 37-37 (2015)

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