推荐产品
质量水平
方案
≥96% (HPLC)
表单
powder
应用
metabolomics
vitamins, nutraceuticals, and natural products
SMILES字符串
CC(C)=CCC[C@](C1C2[C@H](O)CC3[C@@]([C@]2(C)CC1)(C)CCC4C(C)(C)[C@@H](O)CC[C@@]43C)(C)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O
InChI
1S/C36H62O8/c1-20(2)10-9-14-36(8,44-31-30(42)29(41)28(40)23(19-37)43-31)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(39)32(3,4)24(33)12-17-34(25,35)6/h10,21-31,37-42H,9,11-19H2,1-8H3/t21?,22-,23-,24?,25?,26+,27?,28-,29+,30-,31+,33+,34-,35-,36+/m1/s1
InChI key
FVIZARNDLVOMSU-KJULZEBLSA-N
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一般描述
人参皂苷化合物K是在人参根中发现的一种四环达玛烷型三萜皂苷。它是人参的主要成分，人参传统上用于增加对压力和衰老的抵抗力。
应用
- Combination of Electrochemistry and Mass Spectrometry to Study Nitric Oxide Metabolism and Its Modulation by Compound K in Breast Cancer Cells.: This research explores the interaction of Ginsenoside Compound K with nitric oxide metabolism in breast cancer cells, employing a combination of electrochemical techniques and mass spectrometry to elucidate the metabolic pathways and potential therapeutic effects of Compound K (Zhao et al., 2022).
- Metabolic analysis of Panax notoginseng saponins with gut microbiota-mediated biotransformation by HPLC-DAD-Q-TOF-MS/MS.: This article investigates the gut microbiota-mediated biotransformation of Panax notoginseng saponins, including Compound K, detailing the complex interactions and metabolic profiles in a biological system, which could inform their therapeutic use and bioavailability (Chen et al., 2018).
生化/生理作用
人参皂苷化合物K具有很多药理性质，包括抗糖尿病、抗炎、肝脏保护、抗过敏和抗癌作用。它在大鼠中也具有神经保护性质，可以从突触丧失和记忆损害中恢复。人参皂苷化合物K可以抑制人脐静脉内皮细胞（HUVEC）中多种基因表达，从而抑制内皮细胞的迁移和血管生成。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
从最新的版本中选择一种：
Alzheimer's Disease as a Major Public Health Concern: Role of Dietary Saponins in Mitigating Neurodegenerative Disorders and Their Underlying Mechanisms.
Abduljawad, et al.
Molecules (Basel), 27 (2022)
Xi-Ding Yang et al.
Fitoterapia, 100, 208-220 (2014-12-03)
As an intestinal bacterial metabolite of ginseng protopanaxadiol saponins, ginsenoside compound K (20-O-beta-d-glucopyranosyl-20(S)-protopanaxadiol, CK) is a major deglycosylated metabolite form of ginsenosides which is absorbed into the systemic circulation. And it has demonstrated such diverse intriguing biological properties as anticarcinogenic
Effects of sphingolipid metabolism disorders on endothelial cells.
Lai, et al.
Lipids in Health and Disease, 21, 101-101 (2022)
Catherine Hu et al.
European journal of pharmacology, 815, 501-511 (2017-10-17)
Conflicting data exist on the effect of ginsenosides on transactivation of human glucocorticoid receptor α (herein referred to as glucocorticoid receptor), and relatively little is known regarding the effect of these chemicals on transrepression of this receptor. We investigated the
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