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Merck
CN

SMB00313

Sigma-Aldrich

天麻素

≥98% (HPLC)

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别名:
(2R,3S,4S,5R,6S)-2-羟甲基-6-(4-羟甲基-苯氧基)-四氢-吡喃-3,4,5-三醇, 4-β-D-吡喃葡萄糖氧苄醇, 4-羟基苯甲醇 4-O-β-D-葡萄糖苷
经验公式(希尔记法):
C13H18O7
CAS号:
分子量:
286.28
MDL编号:
UNSPSC代码:
12352205
PubChem化学物质编号:
NACRES:
NA.25

生物来源

plant (Gastrodia elata Blume)

质量水平

检测方案

≥98% (HPLC)

形式

powder

应用

detection
metabolomics
vitamins, nutraceuticals, and natural products

储存温度

2-8°C

SMILES字符串

O[C@@H]1[C@@H](CO)O[C@@H](OC2=CC=C(CO)C=C2)[C@H](O)[C@H]1O

InChI

1S/C13H18O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1

InChI key

PUQSUZTXKPLAPR-UJPOAAIJSA-N

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一般描述

天麻素是一种酚性糖苷,是中药复方天麻的主要活性成分。天麻素是兰科植物天麻 Gastrodia elata Blume 的活性成分。

应用

以天麻素为对照,估计 金线莲 叶、根、茎中天麻素的含量。

生化/生理作用

天麻素是一种酚性糖苷,是中药复方天麻的主要活性成分。天麻素可以穿透血脑屏障,并被认为具有抗缺氧的神经保护作用。同时还已知可降低海马组织中γ-氨基丁酸分流酶的免疫反应性。传统意义上,传统上,天麻素还已知可有效治疗头痛、眩晕、头晕和抽搐障碍。除具有抗惊厥作用外,它还具有抗癫痫、抗焦虑、抗炎和抗肥胖作用。天麻素也有助于学习和记忆刺激。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

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Gastrodin protects apoptotic dopaminergic neurons in a toxin-induced Parkinson?s disease model
Kumar H, et al.
Evidence-Based Complementary and Alternative Medicine : ECAM, 2013 (2013)
Tianyuan Ye et al.
International journal of molecular sciences, 19(12) (2018-12-14)
Patients with diabetes mellitus (DM) suffer more risks from diabetic encephalopathy such as cognitive dysfunction and depressive-like behaviors. Numerous studies show that ER (endoplasmic reticulum) stress and inflammation play important roles in the development of diabetic encephalopathy. Gastrodin (Gas), one
Yu Xing et al.
The international journal of biochemistry & cell biology, 109, 8-16 (2019-01-27)
The in vivo protective role of gastrodin (GSTD) in myocardial infarction (MI) has been reported. However, the underlying mechanism remains unclear. Herein, we aimed to explore the effects of GSTD on hypoxia-injured H9c2 cells as well as the downstream microRNAs
Enhanced Agronomic Traits and Medicinal Constituents of Autotetraploids in Anoectochilus formosanus Hayata, a Top-Grade Medicinal Orchid
Chung HH, et al.
Molecules (Basel), 22(11), 1907-1907 (2017)
Man Jiao et al.
Chemosphere, 226, 678-686 (2019-04-09)
The ubiquitous environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has been shown to trigger neurotoxicity. In this study, we investigated the protective effects of gastrodin on TCDD-induced neurotoxicity and the underlying molecular mechanisms. The results show that gastrodin decreased cell viability, tumor necrosis

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