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Merck
CN

SMB00271

Sigma-Aldrich

Chebulinic acid

≥85% (LC/MS-ELSD)

别名:

Eutannin

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About This Item

经验公式(希尔记法):
C41H32O27
CAS号:
分子量:
956.68
UNSPSC代码:
12352205
NACRES:
NA.25

方案

≥85% (LC/MS-ELSD)

表单

solid

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

−20°C

SMILES字符串

O1[C@@H]2[C@H](O[C@H]([C@H](OC(=O)c6c7c(c(c(c6)O)O)OC(=O)[C@H]([C@H]7[C@@H](C1=O)CC(=O)O)O)[C@H]2OC(=O)c5cc(c(c(c5)O)O)O)OC(=O)c4cc(c(c(c4)O)O)O)COC(=O)c3cc(c(c(c3)O)O)O

InChI

1S/C41H32O27/c42-15-1-10(2-16(43)26(15)51)35(56)62-9-22-31-33(66-36(57)11-3-17(44)27(52)18(45)4-11)34(41(63-22)68-37(58)12-5-19(46)28(53)20(47)6-12)67-38(59)13-7-21(48)29(54)32-25(13)24(30(55)40(61)65-32)14(8-23(49)50)39(60)64-31/h1-7,14,22,24,30-31,33-34,41-48,51-55H,8-9H2,(H,49,50)/t14-,22+,24-,30-,31+,33-,34+,41-/m0/s1

InChI key

YGVHOSGNOYKRIH-FJPMMHPYSA-N

一般描述

Natural product derived from plant source.

生化/生理作用

Chebulinic acid is polyphenol that has shown antihypertensive, and anti-oxidant properties. Its antihypertensive effects may be due to decreased cardiac output from reduced left ventricular contraction.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Hyun-Sun Lee et al.
Archives of toxicology, 81(3), 211-218 (2006-08-26)
A hepatoprotective compound was isolated from the ethanolic extract of the fruits of Terminalia chebula Retz. by consecutive solvent partitioning, followed by silica gel and Sephadex LH-20 column chromatographies. The purified compound was identified as a mixture of chebulic acid
Kai Lu et al.
PloS one, 7(8), e43934-e43934 (2012-09-01)
Triphala churna (THL) is a combination of three fruits that has been used for many years in India for the treatment of various diseases. There are now reports which indicate that THL can inhibit growth of malignant tumors in animals.
Zong-Chun Yi et al.
Toxicology in vitro : an international journal published in association with BIBRA, 23(3), 425-431 (2009-04-07)
The prooxidant activity of two hydrolysable tannins, chebulinic acid and tellimagrandin I, on plasmid DNA and genomic DNA of cultured MRC-5 human embryo lung fibroblasts was assessed. The results revealed that both hydrolysable tannins in combination with Cu(II) induced DNA
Zong-chun Yi et al.
Acta pharmacologica Sinica, 25(2), 231-238 (2004-02-11)
To study effects of chebulinic acid on erythroid and megakaryocytic differentiation in K562 cells. The benzidine staining method was used to evaluate hemoglobin synthesis; the expression of erythroid specific glycophorin A (GPA) protein and megakaryocytic surface marker CD61 was determined
Zong-Chun Yi et al.
Toxicology in vitro : an international journal published in association with BIBRA, 23(4), 667-673 (2009-03-31)
The effects of two polyphenols, chebulinic acid and tellimagrandin I, on DNA strand breaks mediated by H(2)O(2)/Cu(II), hydroquinone (HQ)/Cu(II) and H(2)O(2)/Fe(II) in pBR322 plasmid DNA and genomic DNA of cultured MRC-5 human embryo lung fibroblasts were examined. The results demonstrated

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