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Merck
CN

SMB00207

Sigma-Aldrich

Cornuside

≥95% (LC/MS-ELSD)

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About This Item

经验公式(希尔记法):
C24H30O14
分子量:
542.49
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.25

方案

≥95% (LC/MS-ELSD)

表单

solid

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

−20°C

InChI

1S/C24H30O14/c1-3-11-12(4-5-35-21(32)10-6-14(26)17(28)15(27)7-10)13(22(33)34-2)9-36-23(11)38-24-20(31)19(30)18(29)16(8-25)37-24/h3,6-7,9,11-12,16,18-20,23-31H,1,4-5,8H2,2H3/t11-,12+,16+,18+,19-,20+,23+,24-/m0/s1

InChI key

SMTKSCGLXONVGL-ZEIULZLQSA-N

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一般描述

Natural product derived from plant source.

生化/生理作用

Cornuside is a secoiridoid glucoside with anti-inflammatory properties through the downregulation of iNOS and COX-2 via NF-kB inhibition.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Dae Gill Kang et al.
Planta medica, 73(14), 1436-1440 (2007-10-11)
Cornuside is a bisiridoid glucoside compound isolated from the fruit of CORNUS OFFICINALIS Sieb. et Zucc. (Cornaceae). In the present study, we investigated the effect of cornuside on vascular tone in rat aortic tissue. Cornuside induced a concentration-dependent relaxation of
Wang-Lin Jiang et al.
Planta medica, 75(6), 614-619 (2009-03-06)
This study was conducted to investigate the efficacy of cornuside, a secoiridoid glucoside compound, in cultured macrophages as well as in an experimental model of sepsis induced by cecal ligation and puncture (CLP) in rats. Cornuside was added to cultured
Dae Gill Kang et al.
Biological & pharmaceutical bulletin, 30(9), 1796-1799 (2007-09-11)
Cornuside is a bisiridoid glucoside compound isolated from the fruit of Cornus officinalis SIEB. et ZUCC. The present study was designed to examine the effects of cornuside on expression levels of cytokine-induced proinflammatory and adhesion molecules in the human umbilical
Wang-Lin Jiang et al.
Pharmacology, 84(3), 162-170 (2009-08-22)
Cornuside, a secoiridoid glucoside compound, was isolated from the fruit of Cornus officinalis Sieb. et Zucc. The present study elucidates the effects of cornuside on cultured rat cortical neuron damage induced by oxygen-glucose deprivation. The results show that cornuside treatment
Shun Zong Song et al.
Bioscience, biotechnology, and biochemistry, 75(4), 656-661 (2011-04-23)
This study elucidated the effects of cornuside on carbon tetrachloride (CCl₄)-induced hepatotoxicity. Rats were treated intraperitoneally with 0.5 mL/kg of CCl₄. Sixteen h after CCl₄ treatment, the levels of serum aminotransferases, tumor necrosis factor-α (TNF-α), and lipid peroxidation were significantly

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