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Merck
CN

SMB00131

Sigma-Aldrich

3,5-二咖啡酰奎尼酸

≥95% (LC/MS-ELSD)

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别名:
3,5-DCQA, 3,5-Dicaffeoylquinate, 3,5-Dicaffeoylquinic acid, 3,5-O-Dicaffeoylquinic acid, Isochlorogenic Acid A
经验公式(希尔记法):
C25H24O12
CAS号:
分子量:
516.45
MDL编号:
UNSPSC代码:
12352205
PubChem化学物质编号:
NACRES:
NA.25

质量水平

检测方案

≥95% (LC/MS-ELSD)

形式

solid

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

−20°C

SMILES字符串

O[C@H]1[C@@H](C[C@@](O)(C[C@H]1OC(=O)\C=C\c2ccc(O)c(O)c2)C(O)=O)OC(=O)\C=C\c3ccc(O)c(O)c3

InChI

1S/C25H24O12/c26-15-5-1-13(9-17(15)28)3-7-21(30)36-19-11-25(35,24(33)34)12-20(23(19)32)37-22(31)8-4-14-2-6-16(27)18(29)10-14/h1-10,19-20,23,26-29,32,35H,11-12H2,(H,33,34)/b7-3+,8-4+/t19-,20-,23-,25+/m1/s1

InChI key

KRZBCHWVBQOTNZ-PSEXTPKNSA-N

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一般描述

3,5-二咖啡酰奎宁酸是忍冬(Lonicera japonica Thunb)花蕾中的一种酚酸。已用于药理、食品和化妆品研究。

应用

3,5-二咖啡酰奎宁酸已用作高效液相色谱—二极管阵列检测(HPLC-DAD)技术的参考标准品,以定量分析蒿属植物酚类化合物。还用作高效液相色谱-紫外(HPLC-UV)技术的参考标准品,以定量测定菊芋/洋姜(Helianthus tuberosus L./Jerusalem artichoke)中的多酚类化合物。

生化/生理作用

3,5-二咖啡酰奎宁酸可通过抗氧化作用发挥针对体外视网膜损伤的神经保护功能。它是一种强效的麦芽糖酶抑制剂。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Jiahui Chang et al.
Journal of ethnopharmacology, 194, 1032-1042 (2016-11-12)
Houshiheisan (HSHS), a classic traditional medicine prescription, has notable effects on patients with stroke AIM OF THE STUDY: To investigate the neurorestorative effects of HSHS on ischemic stroke and explore its mode of action. Focal cerebral ischemia models were induced
alpha-Glucosidase inhibitory activity by the flower buds of Lonicera japonica Thunb
Zhang Z, et al.,
Journal of functional foods, 5(3), 1253-1259 (2013)
Dilem Tanriseven et al.
Food chemistry, 305, 125505-125505 (2019-10-14)
Shalgam is a beverage which is produced by lactic acid fermentation of black carrot juice. Two commercial methods (traditional method - TM and direct method - DM) used to produce shalgams were compared with respect to their effects on the
Sebastian E W Opitz et al.
Phytochemical analysis : PCA, 28(2), 106-114 (2016-12-23)
Coffee is a widely consumed beverage containing antioxidant active compounds. During roasting the phytochemical composition of the coffee bean changes dramatically and highly polymeric substances are produced. Besides chlorogenic acids that are already present in green coffee beans, melanoidins show
Water extract of propolis and its main constituents, caffeoylquinic acid derivatives, exert neuroprotective effects via antioxidant actions
Nakajima Y, et al.,
Life Sciences, 80(4), 370-377 (2007)

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