推荐产品
产品名称
Proteasome Substrate,
方案
≥95% (HPLC)
表单
lyophilized
组成
Peptide Content, ≥87%
储存条件
protect from light
储存温度
−20°C
Amino Acid Sequence
Z-Gly-Gly-Leu-AMC
应用
Z-Gly-Gly-Leu-7-amido-4-methylcoumarin (Z-Gly-Gly-Leu-AMC) has been used as a substrate for proteasome peptidase to measure proteosome activities using spectrophotometer.
生化/生理作用
Z-Gly-Gly-Leu-7-amido-4-methylcoumarin (Z-Gly-Gly-Leu-AMC) is a fluorogenic peptide that is used in analysis of protease and peptidase activity of proteasomes. Z-GGL-AMC has been noted as a particular substrate for chymotrypsin-like activity. It has low solubility and precipitates at 100μM.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Raymond J. Deshaies
Ubiquitin and Protein Degradation, Part 1, 1 null
S Rathore et al.
Cell death & disease, 2, e231-e231 (2011-11-25)
The ATP-dependent ClpQY protease system in Plasmodium falciparum is a prokaryotic machinery in the parasite. In the present study, we have identified the complete ClpQY system in P. falciparum and elucidated its functional importance in survival and growth of asexual
S G Roudiak et al.
Biochemistry, 37(1), 377-386 (1998-02-07)
We have charterized a Mycobacterium smegmatis gene encoding a homolog of the ATP-dependent protease Lon (La). Our identification of a Lon homolog, in conjunction with our previous work, identifies M. smegmatis as the first known example of a eubacterium containing
C P Ma et al.
The Journal of biological chemistry, 267(15), 10515-10523 (1992-05-25)
A protein that greatly stimulates the multiple peptidase activities of the 20 S proteasome (also known as macropain, the multicatalytic protease complex, and 20 S protease) has been purified from bovine red blood cells and from bovine heart. The activator
Tumor necrosis factor-a sensitizes breast cancer cells to natural products with proteasome-inhibitory activity leading to apoptosis.
Lu L
PLoS ONE, 9(11), e113783-e113783 (2014)
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