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Merck
CN
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主要文件

安全信息

SCP0122

Sigma-Aldrich

[Des-Tyr22]-Calcitonin salmon

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About This Item

经验公式(希尔记法):
C136H231N43O46S2
分子量:
3268.68
UNSPSC代码:
12352209
NACRES:
NA.32

方案

≥95% (HPLC)

表单

lyophilized

组成

Peptide Content, ≥75%

储存条件

protect from light

储存温度

−20°C

相关类别

Amino Acid Sequence

Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2

应用

Calcitonin, a 32 amino acid polypeptide, is involved in the regulation of calcium and phosphorous metabolism often antagonistic to parathyroid hormone (PTH). [Des-Tyr22]-Calcitonin salmon (Des-Tyr22-sCT) is an analogue of calcitonin with decreased in vitro adenylate cyclase activation activity and inhibitory activity for prolactin release from isolated rat pituitary cells.

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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R M Epand et al.
Journal of medicinal chemistry, 31(8), 1595-1598 (1988-08-01)
Salmon calcitonin has an amino acid sequences that would allow it to form an amphipathic helix from approximately residue 9 to residue 22. We have synthesized a number of analogues of this peptide hormone with deletions in the carboxyl terminus

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