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检测方案
≥95% (HPLC)
形式
lyophilized
组成
Peptide Content, ≥68%
储存条件
protect from light
储存温度
−20°C
Amino Acid Sequence
Trp-Ser-Lys-Met-Asp-Gln-Leu-Ala-Lys-Glu-Leu-Thr-Ala-Glu
应用
Chromogranin A (parathyroid secretory protein 1) is a precursor of the vasostatin, pancreastatin, catestatin, parastatin, chromostatin, GE-25 and WE-14. WE 14 is used to search for its as yet undefined physiological roles.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
Per-Gøran Krüger et al.
Regulatory peptides, 114(1), 29-35 (2003-05-24)
Catestatin (bovine CgA(344-364)) is a cationic peptide, which besides reducing catecholamine secretion from chromaffin cells in vitro also acts a potent vasodilator in the rat in vivo. The alleged histamine releasing effect of catestatin was tested in vitro in rat
William James Curry et al.
Microscopy research and technique, 62(5), 408-414 (2003-11-06)
WE-14 is generated in subpopulations of chromogranin A immunopositive endocrine cells and neurons including those innervating the anterior uvea. This study investigated WE-14 in intact sclero-limbo-corneal tissue from embryonic (E17), neonatal (N0-N16), and adult mice using immunocytochemistry and confocal scanning
W J Curry et al.
Annals of the New York Academy of Sciences, 971, 311-316 (2002-11-20)
The neuropeptide WE-14 is derived from the posttranslational processing of chromogranin A (CgA). While CgA is expressed in a preponderance of neuroendocrine cells, WE-14 is generated in a distinct subpopulation of CgA-immunopositive cells, most notably in the adrenal, pituitary, and
The modulatory effects of WE-14 on histamine release from rat peritoneal mast cells.
P Forsythe et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 46 Suppl 1, S13-S14 (1997-03-01)
Carmel Mary McVicar et al.
Regulatory peptides, 115(1), 1-10 (2003-07-23)
Immunohistochemical analysis of the male and female rat adenohypophysis revealed that chromogranin A (CgA), beta-granin and WE-14 immunostaining was localised to follicle stimulating hormone (FSH) producing cells, while luteinizing hormone (LH) producing cells exhibited chromogranin A and beta-granin immunostaining. The
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