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Merck
CN
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文件

安全信息

SCP0111

Sigma-Aldrich

Cell Adhesion Inhibitor Peptide

≥95% (HPLC), lyophilized powder, cyclic

别名:

cyloRGDfV

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About This Item

经验公式(希尔记法):
C26H38N8O7
分子量:
574.63
UNSPSC代码:
12352202
NACRES:
NA.32

product name

Cell Adhesion Inhibitor Peptide, cyclic,

检测方案

≥95% (HPLC)

形式

lyophilized

组成

Peptide Content, ≥75%

储存条件

protect from light

储存温度

−20°C

Amino Acid Sequence

Arg-Gly-Asp-Phe-Val

应用

Cyclic RGDFV (cyloRGDfV) is an RGD containing peptide antagonist, with specificity for α(V)β(3) integrin, that is used to inhibit the binding of cells to RGD proteins such as vitronectin.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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Warren B Nothnick et al.
PloS one, 9(6), e100336-e100336 (2014-06-18)
Endometriosis is defined as the growth of endometrial glandular and stromal components in ectopic locations and affects as many as 10% of all women of reproductive age. Despite its high prevalence, the pathogenesis of endometriosis remains poorly understood. MicroRNAs, small
Joel D Pearson et al.
Cancer cell, 39(8), 1115-1134 (2021-07-17)
Cancer heterogeneity impacts therapeutic response, driving efforts to discover over-arching rules that supersede variability. Here, we define pan-cancer binary classes based on distinct expression of YAP and YAP-responsive adhesion regulators. Combining informatics with in vivo and in vitro gain- and loss-of-function studies
Damien Garbett et al.
Nature communications, 11(1), 4818-4818 (2020-09-25)
Migrating cells move across diverse assemblies of extracellular matrix (ECM) that can be separated by micron-scale gaps. For membranes to protrude and reattach across a gap, actin filaments, which are relatively weak as single filaments, must polymerize outward from adhesion

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