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Merck
CN
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主要文件

安全信息

SCP0105

Sigma-Aldrich

Caspase Substrate, chromogenic

≥95% (HPLC), lyophilized

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About This Item

经验公式(希尔记法):
C31H43N9O14
分子量:
765.73
UNSPSC代码:
12352202
NACRES:
NA.32

产品名称

Caspase Substrate, chromogenic,

方案

≥95% (HPLC)

表单

lyophilized

组成

Peptide Content, ≥75%

储存条件

protect from light

储存温度

−20°C

Amino Acid Sequence

Ac-Val-Asp-Gln-Gln-Asp-pNA

应用

Ac-VDQQD-pNA (acetyl-Val-Asp-Gln-Gln-Asp-p-nitroanilide) is used as a chromogenic caspase substrate.

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Vasoactive intestinal peptide inhibits TNF-α-induced apoptotic events in acinar cells from nonobese diabetic mice submandibular glands.
Calafat M, Larocca L, Roca V, Hauk V, et al.
Arthritis Research, 11, R53-R53 (2009)
Gary K Smith et al.
Archives of biochemistry and biophysics, 399(2), 195-205 (2002-03-13)
Because of the intimate role of caspase-8 in apoptosis signaling pathways from FAS, TNFR1, and other death receptors, the enzyme is a potentially important therapeutic target. We have generated an Escherichia coli expression construct for caspase-8 in which a His-tag
Natasha Ann Pereira et al.
Biochemical and biophysical research communications, 377(3), 873-877 (2008-11-04)
Many designated substrates and inhibitors have been widely used to investigate the roles of caspases in apoptotic death during mammalian cell culture. However, the specificities of these substrates and inhibitors have not been systematically evaluated. As a result, conclusions on

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