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检测方案
≥95% (HPLC)
形式
lyophilized
组成
Peptide Content, ≥80%
储存条件
protect from light
储存温度
−20°C
Amino Acid Sequence
Ac-Leu-Glu-Val-Asp-al
应用
Caspase 4 Inhibitor (Ac-LEVD-CHO) is used for the selective inhibition of caspase 4 to differentiate its role in specific cell apoptosis pathways.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Zong-Mei Bian et al.
Investigative ophthalmology & visual science, 50(12), 6006-6014 (2009-08-01)
To investigate the functional involvement of caspase-4 in human retinal pigment epithelial (hRPE) cells. Expression and activation of caspase-4 in hRPE cells were measured after stimulation with proinflammatory agents IL-1beta (2 ng/mL), TNF-alpha (20 ng/mL), lipopolysaccharide (1000 ng/mL), interferon-gamma (500
Akiko Yamamuro et al.
Journal of pharmacological sciences, 115(2), 239-243 (2011-02-02)
The present study investigated the function of caspase-4 in endoplasmic reticulum (ER) stress-induced apoptosis in human neuronal cell line SH-SY5Y. Tunicamycin, which is known to induce ER stress, activated both caspase-9 and caspase-4, and the activation of caspase-4 preceded that
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