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Merck
CN
所有图片(1)

文件

安全信息

SCP0059

Sigma-Aldrich

Calcitonin Acetyl salmon

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经验公式(希尔记法):
C147H242N44O49S2
分子量:
3473.89
UNSPSC代码:
51111800
NACRES:
NA.77

检测方案

≥95% (HPLC)

形式

lyophilized

组成

Peptide Content, ≥75%

储存条件

protect from light

储存温度

−20°C

Amino Acid Sequence

Ac-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2

应用

Calcitonin, a 32 amino acid polypeptide, is involved in the regulation of calcium and phosphorous metabolism often antagonistic to parathyroid hormone (PTH).

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral

WGK

WGK 3

法规信息

监管及禁止进口产品

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Claudia Mueller et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 79(3), 646-657 (2011-06-28)
Protein aggregation, which is triggered by various factors, is still one of the most prevalent problems encountered during all stages of protein formulation development. In this publication, we present novel excipients, tryptophan-mPEGs (Trp-mPEGs) of 2 and 5 kDa molecular weight
Aiwen Huang et al.
Drug delivery, 18(8), 562-569 (2011-08-10)
Therapeutic peptide and protein drugs have high specificity and activity in their functions but present challenges in their administration route, requiring development of new delivery systems to improve their bioavailability. The aim of this work was to investigate the role
Synthesis, characterization and evaluation of bone targeting salmon calcitonin analogs in normal and osteoporotic rats.
Bhandari KH, Newa M, Chapman J, et al.
J. Controlled Release, 158, 44-52 (2012)
Cetin Tas et al.
International journal of pharmaceutics, 423(2), 257-263 (2011-12-17)
Peptides and polypeptides have important pharmacological properties but only a limited number have been exploited as therapeutics because of problems related to their delivery. Most of these drugs require a parenteral delivery system which introduces the problems of pain, possible

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