跳转至内容

尊敬的客户：

目前国际形势复杂多变，关税政策尚不明朗，这可能对我们的产品价格产生一定影响。在此情况下，我们希望就订单事宜与您进行友好沟通。

基于当前的不确定性，如果您选择在此期间下单，我们将保留根据实际情况调整价格的权利。同时，我们也理解市场变化可能给您带来的困扰，因此如果在订单实际发货前因关税政策变动导致价格出现较大波动，默克将与您进行协商讨论并视情况对订单进行调整或取消。

关于应对近期政策变化的重要更新，请点击此处查看详情。

Merck
CN
所有图片(2)

主要文件

查看所有文档

SBR00065

Sigma-Aldrich

Rifampicin Ready Made Solution

50 mg/mL in DMSO

登录查看公司和协议定价
所有图片(2)

About This Item

经验公式（希尔记法）:
C43H58N4O12
CAS号:
13292-46-1
分子量:
822.94
UNSPSC代码:
41116107
NACRES:
NA.76
价格与库存信息目前不能提供

表单

liquid

质量水平

200

比活

Antibacterial

浓度

50 mg/mL in DMSO

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria
mycobacteria
viruses

作用机制

protein synthesis | interferes

储存温度

−20°C

SMILES字符串

N5(CCN(CC5)C)\N=C\c1c2c(c3c(c4c(c(c3O)C)O[C@](O\C=C\[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]([C@H](\C=C\C=C(/C(=O)N2)\C)C)O)C)O)C)OC(=O)C)C)OC)(C4=O)C)c1O)O

InChI

1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1

InChI key

JQXXHWHPUNPDRT-WLSIYKJHSA-N

一般描述

Rifampicin is a microlide antibiotic effective against gram-positive and gram-negative bacteria, mycobacteria and viruses.

应用

  • Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. [1]
  • Rifampicin is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, and primary biliary cirrhosis (PBC).[2]
  • Rifampicin was also found active by inhibiting Tau Oligomer Propagation in Alzheimer’s disease. [3]
  • Rifampicin is used as a selection agent for agrobacterium mediated plant transformation. [4]

生化/生理作用

Inhibits the assembly of DNA and protein into mature virus particles.
Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase.

其他说明

The product is supplied in DMSO at a concentration of 50 mg/mL. Working concentrations for agrobacterium selection are typically 10-50 mg/L.

危险声明

H362

危险分类

Lact.

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

188.6 °F - closed cup

闪点(°C)

87 °C - closed cup

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    0000411085
    0000411085
    0000345737
    0000328305
    0000328305

    没有发现合适的版本？

    如果您需要特殊版本，可通过批号或批次号查找具体证书。

    搜索COA

    已有该产品？

    在文件库中查找您最近购买产品的文档。

    访问文档库

    Specific packaging of custom RNA molecules into cowpea mosaic virus-like particles
    Peyret, Hadrien, et al
    Methods in Molecular Biology, 103-111 (2022)
    Guidelines for the Management of Cholestatic Liver Diseases (2021)
    Lu, Lungen
    Journal of clinical and translational hepatology (2022)
    Treatment of rifampicin-resistant tuberculosis disease and infection in children: key updates, challenges and opportunities
    Howell, Pauline, et al.
    Pathogens (Basel, Switzerland), 11.4, 381-381 (2022)
    Nasal Rifampicin Halts the Progression of Tauopathy by Inhibiting Tau Oligomer Propagation in Alzheimer Brain Extract-Injected Mice
    Umeda, Tomohiro, et al
    Biomedicines, 10.2, 297-297 (2022)

    我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

    联系客户支持