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一般描述
This product is the pre-hydrolyzed form of the Styrene:Maleic Anhydride Copolymer 1:1. It can be regarded, in effect, as Styrene:Maleic Acid Copolymer 1:1 (SMA Copolymer 1:1).
应用
Lipodisq reagents are novel polymers derived from styrene and maleic acid. Lipodisq polymers are capable of forming nanosized lipid-based discoidal particles capable of incorporating membrane proteins. The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents. Lipodisqs typically have a diameter of 9-10 nm at pH 7.4.
The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents.
Functional pH range: 3.5 - 5.5
The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents.
Functional pH range: 3.5 - 5.5
法律信息
Lipodisq is a registered trademark of Malvern Cosmeceutics Limited
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Juan Francisco Bada Juarez et al.
Chemistry and physics of lipids, 221, 167-175 (2019-04-04)
Nanoparticles assembled with poly(styrene-maleic acid) copolymers, identified in the literature as Lipodisq, SMALPs or Native Nanodisc, are routinely used as membrane mimetics to stabilise protein structures in their native conformation. To date, transmembrane proteins of varying complexity (up to 8
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