质量水平
储存温度
room temp
一般描述
Lipodisq纳米颗粒通常由苯乙烯马来酸（SMA）共聚物和磷脂组成。它具有与纳米圆盘几乎相似的结构。Lipodisq纳米颗粒被认为是用于膜蛋白结构研究的良好膜模拟系统。
应用
Lipodisq试剂是来源于苯乙烯和马来酸的新型聚合物。 Lipodisq聚合物能够形成可在膜蛋白中结合的纳米脂质盘状颗粒。 Lipodisq技术可以在不使用表面活性剂的情况下溶解常用的脂质，例如二肉豆蔻酰磷脂酰胆碱（DMPC）。 在pH 7.4下，Lipodisqs的直径通常为9-10 纳米。
Lipodisq技术可以在不使用表面活性剂的情况下溶解常用的脂质，例如二肉豆蔻酰磷脂酰胆碱（DMPC）。
功能pH范围： 5.5 - 8.0
Lipodisq技术可以在不使用表面活性剂的情况下溶解常用的脂质，例如二肉豆蔻酰磷脂酰胆碱（DMPC）。
功能pH范围： 5.5 - 8.0
生化/生理作用
Lipodisq纳米颗粒被认为是用于膜蛋白结构研究的良好膜模拟系统。
包装
100、500 mg 聚乙烯瓶封装
法律信息
Lipodisq is a registered trademark of Malvern Cosmeceutics Limited
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Characterization of the structure of lipodisq nanoparticles in the presence of KCNE1 by dynamic light scattering and transmission electron microscopy
Zhang R, et al.
Chemistry and Physics of Lipids, 203, 19-23 (2017)
Characterization of KCNE1 inside lipodisq nanoparticles for EPR spectroscopic studies of membrane proteins
Sahu I D, et al.
The Journal of Physical Chemistry B, 121(21), 5312-5321 (2017)
Lina Zhu et al.
PeerJ, 10, e13381-e13381 (2022-05-10)
Smoothened (SMO) protein is a member of the G protein-coupled receptor (GPCR) family that is involved in the Hedgehog (Hh) signaling pathway. It is a putative target for treating various cancers, including medulloblastoma and basal cell carcinoma (BCC). Characterizing membrane
Juan Francisco Bada Juarez et al.
Biochimica et biophysica acta. Biomembranes, 1862(3), 183152-183152 (2019-12-18)
Dopamine receptors (DRs) are class A G-Protein Coupled Receptors (GPCRs) prevalent in the central nervous system (CNS). These receptors mediate physiological functions ranging from voluntary movement and reward recognition to hormonal regulation and hypertension. Drugs targeting dopaminergic neurotransmission have been
Juan Francisco Bada Juarez et al.
Chemistry and physics of lipids, 221, 167-175 (2019-04-04)
Nanoparticles assembled with poly(styrene-maleic acid) copolymers, identified in the literature as Lipodisq, SMALPs or Native Nanodisc, are routinely used as membrane mimetics to stabilise protein structures in their native conformation. To date, transmembrane proteins of varying complexity (up to 8
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