SAB6012473
KD-Validated Anti BAG cochaperone 3 Antibody, clone 23GB1520, Rabbit Monoclonal
clone 23GB1520, recombinant rabbit monoclonal, expressed in HEK293 cells
别名:
BAG-3, BIS, CAIR-1, MFM6
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UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
23GB1520, recombinant monoclonal
Application:
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Species reactivity:
human
Citations:
Technique(s):
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
Uniprot accession no.:
产品名称
KD-Validated Anti BAG cochaperone 3 Antibody, clone 23GB1520, Rabbit Monoclonal, clone 23GB1520, recombinant rabbit monoclonal, expressed in HEK293 cells
biological source
rabbit (Monoclonal)
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
23GB1520, recombinant monoclonal
form
buffered aqueous glycerol solution
mol wt
62 kDa
species reactivity
human
packaging
vial of 1.5 mL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
Quality Level
Gene Information
human ... BAG3(9531)
sustainability
Greener Alternative Product
concentration
0.25 mg/ml
technique(s)
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
isotype
IgG
Ensembl | human accession no.
NCBI accession no.
UniProt accession no.
greener alternative category
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
We are committed to bringing you Greener Alternative Products. This product is a Design for Sustainability (DfS) developed product, which belongs to one of the four categories of greener alternatives. Click here to view its DfS scorecard.
Immunogen
A synthesized peptide corresponding to a sequence within amino acids 60-130 of human Bag3 [NP_004272.2].
Other Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Physical form
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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