biological source
rabbit
conjugate
unconjugated
material
colorless
clone
1O3A4, monoclonal
form
liquid
species reactivity
human, rat, rat
concentration
0.5 mg/mL
technique(s)
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
FGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MMP12(4321)
Application
WB
General description
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 371-470 of human MMP12 (P39900).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
存储类别
10 - Combustible liquids
wgk
WGK 1
法规信息
常规特殊物品
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