Anti-HOXA13 Antibody, clone 5K0D5, Rabbit Monoclonal

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. [provided by RefSeq, Jul 2008]

A synthetic peptide corresponding to a sequence within amino acids 250-350 of human HOXA13 (P31271).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

WB