SAB5702685
Anti-CRK/CRKII Antibody, clone 4Y2C2, Rabbit Monoclonal
别名:
CRKII, p38
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关于此项目
NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
mouse
Technique(s):
western blot: 1:500 - 1:2000
Application:
WB
Citations:
-
species reactivity
mouse
concentration
1.01mg/mL
technique(s)
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPAL
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
4Y2C2, monoclonal
form
liquid
mol wt
37 kDa
Quality Level
Gene Information
human ... CRK(1398)
General description
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CRK/CRKII (P46108).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB
存储类别
10 - Combustible liquids
wgk
WGK 1
法规信息
常规特殊物品
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