Anti-14-3-3 Theta Antibody, clone 9G6M4, Rabbit Monoclonal

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human 14-3-3 Theta (P27348).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

WB, IF/ICC