Anti-SIRT6 Antibody, clone 1D0L6, Rabbit Monoclonal

This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

A synthetic peptide corresponding to a sequence within amino acids 256-355 of human SIRT6 (Q8N6T7).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

WB