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Merck
CN
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主要文件

安全信息

SAB5702155

Sigma-Aldrich

Anti-NeuN Antibody, clone 3M5M9, Rabbit Monoclonal

别名:

FOX-3,FOX3,HRNBP3,NEUN,NeuN,RBFOX3

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.46

生物来源

rabbit

质量水平

物料

colorless

克隆

3M5M9, monoclonal

表单

liquid

分子量

46-55 kDa

种属反应性

rat, rat, human

浓度

1.00 mg/mL

技术

immunofluorescence: 1:50 - 1:200
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:1000

颜色

colorless

同位素/亚型

IgG

免疫原序列

MAQPYPPAQYPPPPQNGIPAEYAPPPPHPTQDYSGQTPVPTEHGMTLYTPAQTHPEQPGSEASTQPIAGTQTVPQTDEAAQTDSQPLHPSDPTEKQQPKR

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... RBFOX3(146713)

一般描述

This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NeuN (A6NFN3).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

应用

WB, IHC, IF/ICC

象形图

Exclamation markEnvironment

警示用语:

Warning

危险声明

危险分类

Aquatic Chronic 2 - Skin Sens. 1

储存分类代码

10 - Combustible liquids

WGK

WGK 3

法规信息

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