生物来源
rabbit
质量水平
物料
colorless
克隆
7Y9M2, monoclonal
表单
liquid
分子量
34 kDa
种属反应性
rat, human, rat
浓度
1.5 mg/mL
技术
immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:2000
颜色
colorless
同位素/亚型
IgG
免疫原序列
MESQEPTESSQNGKQYIISEELISEGKWVKLEKTTYMDPTGKTRTWESVKRTTRKEQTADGVAVIPVLQRTLHYECIVLVKQFRPPMGGYCIEFPAGLID
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... NUDT5(11164)
一般描述
This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors.
免疫原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NUDT5 (Q9UKK9).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
应用
WB, IF/ICC
储存分类代码
10 - Combustible liquids
WGK
WGK 1
法规信息
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