推荐产品
生物来源
rabbit
质量水平
抗体产品类型
primary antibodies
克隆
polyclonal
表单
liquid
种属反应性
mouse, rat, human
浓度
2.37 mg/mL
技术
immunohistochemistry: 1:50-1:100
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
phosphorylation (pTyr1054/pTyr1055)
基因信息
human ... Tyk2(7297)
一般描述
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
免疫原
A synthetic phosphorylated peptide around Y1054 & Y1055 of human Tyk2 (NP_003322.3).
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
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