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安全信息

SAB5701767

Sigma-Aldrich

Anti-Phospho-α-Synuclein-S129 antibody produced in rabbit

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.43

生物来源

rabbit

质量水平

抗体产品类型

primary antibodies

克隆

polyclonal

形式

liquid

种属反应性

human

浓度

1.35 mg/mL

技术

western blot: 1:500-1:1000

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

phosphorylation (pSer129 )

基因信息

human ... SNCA(6622)

一般描述

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer′s disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.

免疫原

A phospho specific peptide corresponding to residues surrounding S129 of human alpha-Synuclein

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

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WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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