Anti-Phospho-STAT4-Y693 antibody produced in rabbit

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

A phospho specific peptide corresponding to residues surrounding Y693 of human STAT4

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.