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SAB5701501

Sigma-Aldrich

Anti-CD59 antibody produced in rabbit

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1 EA
¥489.23

¥489.23


预计发货时间2025年4月10日详情



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1 EA
¥489.23

About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

¥489.23


预计发货时间2025年4月10日详情


生物来源

rabbit

质量水平

抗体产品类型

primary antibodies

克隆

monoclonal

表单

liquid

种属反应性

human

浓度

0.2 mg/mL

技术

immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

UniProt登记号

运输

wet ice

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WH0007327M1WH0007321M1WH0007325M1
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

Gene Information

human ... UBE2H(7328)

Gene Information

human ... UBE2G2(7327)

Gene Information

human ... UBE2D1(7321)

Gene Information

human ... UBE2E2(7325)

clone

3C4-1A2, monoclonal

clone

5E1, monoclonal

clone

2C6, monoclonal

clone

4B4, monoclonal

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

一般描述

This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

免疫原

A synthesized peptide derived from human CD59

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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