¥489.23
预计发货时间2025年4月10日详情
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此商品 | WH0007327M1 | WH0007321M1 | WH0007325M1 |
|---|---|---|---|
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| biological source mouse | biological source mouse | biological source mouse | biological source mouse |
| Gene Information human ... UBE2H(7328) | Gene Information human ... UBE2G2(7327) | Gene Information human ... UBE2D1(7321) | Gene Information human ... UBE2E2(7325) |
| clone 3C4-1A2, monoclonal | clone 5E1, monoclonal | clone 2C6, monoclonal | clone 4B4, monoclonal |
| species reactivity human | species reactivity human | species reactivity human | species reactivity human |
一般描述
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
免疫原
A synthesized peptide derived from human CD59
外形
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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