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安全信息

SAB5701337

Sigma-Aldrich

Anti-PIM1 antibody produced in rabbit

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UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体产品类型

primary antibodies

克隆

monoclonal

形式

liquid

种属反应性

rat, human, mouse

浓度

0.6 mg/mL

技术

immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... PIM1(5292)

一般描述

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]

免疫原

A synthesized peptide derived from human PIM1.

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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