生物来源
rabbit
质量水平
抗体产品类型
primary antibodies
克隆
monoclonal
形式
liquid
种属反应性
rat, human, mouse
浓度
2.05 mg/mL
技术
immunohistochemistry: 1:50-1:200
western blot: 1:5000-1:8000
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... DNMT1(1786)
一般描述
This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
免疫原
A synthesized peptide derived from human DNMT1.
外形
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
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WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
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