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安全信息

SAB5701086

Sigma-Aldrich

Anti-CD86 antibody produced in rabbit

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UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体产品类型

primary antibodies

克隆

polyclonal

形式

liquid

种属反应性

human, rat, mouse

浓度

2.4 mg/mL

技术

immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... CD86(942)

一般描述

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

免疫原

Recombinant protein of human CD86.

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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