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安全信息

SAB5700919

Sigma-Aldrich

Anti-MMP13 antibody produced in rabbit

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UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体产品类型

primary antibodies

克隆

monoclonal

形式

liquid

种属反应性

rat, human, mouse

浓度

0.8 mg/mL

技术

western blot: 1:500-1:2000

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... MMP13(4322)

一般描述

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]

免疫原

A synthesized peptide derived from human MMP13

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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